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Transgenic drugs could help hemophilia
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SCIENTISTS are developing new drugs for treating hemophilia using transgenic technology at a research and development center in Songjiang District.
Zeng Fanyi, director of the Institute of Medical Genetics at the Shanghai Children’s Hospital, told the closing ceremony of the Shanghai Health and Science Week yesterday transgenic technology allowed the blood clotting factor Prothrombin Complex Concentrate be extracted for treating hemophilia.
Zeng is also a chief scientist with the National Basic Research Program of China.
Zeng said hemophiliacs are currently mainly treated by transfusing blood plasma clotting factors or the prothrombin complex.
But the sources of these blood products are limited and pose the risk of hepatitis infection. Foreign recombinant PCC products are expensive.
Zeng’s team has been doing research on extracting PCC from special transgenic milk for 20 years.
With transgenic technologies, scientists use the mammary glands of cows and ewes as a bioreactor and get milk containing special proteins, which can be recombined to form the pharmaceutical proteins people require.
They are now applying for the go-ahead for a clinical test and researching the commercialization of the “mammary gland bioreactor” technology.
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