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Fudan team develops antibody
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RESEARCHERS from Shanghai’s Fudan University said yesterday that they had been working with US experts since 2013 to develop an antibody that may be able to block or treat the MERS virus.
There are currently no effective therapies against the Middle East Respiratory Syndrome virus, but the Fudan team said it may have come up with a promising candidate.
Researchers from Fudan’s School of Basic Medicine said the antibody they have developed with the US-based National Institutes of Health — m336 — was able to kill the MERS virus in tests on animals.
Dr Zhong Nanshan, China’s leading expert on respiratory diseases, said antibody therapy can be effective and called for a quick launch of clinical studies and trials.
Jiang Shibo, head of the antibody research team, said yesterday: “Several universities in the world are also doing anti-MERS antibody research, while ours is the first to finish the test on animal models and its effects are better than others.”
In addition to the antibody, Jiang’s team has also developed an anti-MERS spray — HR2P-M2 — which tests have shown can greatly reduce the virus count in affected animals when given through the nose.
“It is a good preventative measure for those at high risk, such as medical staff, as the MERS virus usually affects the nasal passage and the lungs,” Jiang said.
He said that studies had also shown that a combination of HR2P-M2 and m336 could have an even greater effect on MERS.
The team said that it had reported its latest findings to the National Health and Family Planning Commission.
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